H2AFZ polyclonal (C-term), anti-human

H2AFZ polyclonal (C-term), anti-human

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In stock
SKU
AC-AP11237b
Catalog Number: AC-AP11237b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB20139
Applications: WB, IHC-P
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Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq].

Other Names:
Histone H2AZ, H2A/z, H2AFZ, H2AZ

Target/Specificity:
This H2AFZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the C-terminal region of human H2AFZ.

Antigen Region:
59-86

Antigen Type: Synthetic Peptide

Gene Name: H2AZ1 (HGNC:4741)
Gene ID: 3015
Primary Accession: P0C0S5
NCBI Accession: NP_002097.1
Other Accession: P0C0S7; P0C0S6; Q5ZMD6; P0C0S4; Q6GM74; O62695; Q3THW5; Q71UI9; P08985; Q71PD7; P02272; Q27511; Q32LA7; NP_002097; Q6YNC8
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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