H2BFS polyclonal (Center), anti-human

H2BFS polyclonal (Center), anti-human

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In stock
SKU
AC-AP18574c
Catalog Number: AC-AP18574c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB30487
Applications: WB
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Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.

Other Names:
Histone H2B type F-S, Histone H2Bs, H2B/s, H2BFS

Target/Specificity:
This H2BFS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-84 amino acids from the Central region of human H2BFS.

Antigen Region:
58-84

Antigen Type: Synthetic Peptide

Gene Name: H2BC12L (HGNC:4762)
Gene ID: 102724334
Primary Accession: P57053
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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