H3F3B Polyclonal Antibody

Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
H3 histone family 3A, H3 histone family 3B, H3 histone, family 3B (H3.3B), H3.3, H3.3A, H3.3B, H33, H3F3, H3F3A, H3f3b, Histone H3.3, Histone H3.3Q, Histone H3.A, Histone H3.B, MGC87782, MGC87783

Immunogen: Fusion protein of human H3F3B

Swissprot: P84243
Gene Accession: BC001124

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.72 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.