HADHA Polyclonal Antibody

Background:
This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction, Tags and Cell Markers

Synonyms:
HADHA, ECHA, GBP, HADH, LCEH, LCHAD, MTPA, TP-ALPHA

Immunogen: Recombinant fusion protein of human HADHA (NP_000173.2).

Swissprot: P40939
Gene ID: 3030

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.