HAMP Polyclonal Antibody

Background:
Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages.Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa.

Research Area: Cancer, Cardiovascular, Metabolism, Signaling transduction

Synonyms:
Hamp, HEPC, HEPC, Hepc20, Hepc25, HEPCIDIN, Hepcidin 20, Hepcidin 25, Hepcidin antimicrobial peptide, Hepcidin-20, Hepcidin25, HFE2, HFE2B, LEAP 1, LEAP-1, LEAP1, Liver expressed antimicrobial peptide, Liver-expressed antimicrobial peptide 1, PLTR, Putative liver tumor regressor

Immunogen: Recombinant Human Hepcidin protein

Swissprot: P81172

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Concentration: 2 mg/mL
Dilution: IHC 1:50-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.