HAMP polyclonal (Center), anti-human

HAMP polyclonal (Center), anti-human

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In stock
SKU
AC-AP9459C
Catalog Number: AC-AP9459C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB22098
Applications: WB
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Background:
HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity.

Other Names:
Hepcidin, Liver-expressed antimicrobial peptide 1, LEAP-1, Putative liver tumor regressor, PLTR, Hepcidin-25, Hepc25, Hepcidin-20, Hepc20, HAMP, HEPC, LEAP1

Target/Specificity:
This HAMP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the Central region of human HAMP.

Antigen Region:
17-46

Antigen Type: Synthetic Peptide

Gene Name: HAMP (HGNC:15598)
Gene ID: 57817
Primary Accession: P81172
NCBI Accession: NP_066998.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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