HAND1 Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.

Synonyms:
autonomic nervous system and neural crest derivatives-expressed protein 1, Basic helix loop helix transcription factor HAND1, bHLHa27, Class A basic helix-loop-helix protein 27, eHAND, Extraembryonic tissues, Extraembryonic tissues heart autonomic nervous system and neural crest derivatives expressed protein 1, HAND 1, HAND1, HAND1, Heart and neural crest derivatives expressed 1, Heart and neural crest derivatives expressed protein 1, heart, Heart- and neural crest derivatives-expressed protein 1, Hxt, Thing 1, Thing1 , Thing1

Immunogen: Synthetic peptide of human HAND1

Swissprot: O96004
Gene Accession: NP004812

Calculated MW: 24 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.9 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.