HAND2 Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.

Research Area: Cardiovascular, Epigenetics and Nuclear Signaling, Neuroscience

Synonyms:
HAND2, DHAND2, Hed, Thing2, bHLHa26, dHand

Immunogen: Recombinant fusion protein of human HAND2 (NP_068808.1).

Swissprot: P61296
Gene ID: 9464

Calculated MW: 20 kDa/23 kDa
Observed MW: 26 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.