HAP1 polyclonal, anti-human

Background:
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Other Names:
Huntingtin-associated protein 1, HAP-1, Neuroan 1, HAP1, HAP2, HLP1

Antigen Types:
Synthetic Peptide

Gene Name:
HAP1
Gene ID:
9001
Primary Accession: P54257
Other Accession: NP_817084;9001;