Haptoglobin / HP polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6628
Background:
Haptoglobin (Hp) is a blood plasma protein that functions to bind free Hemoglobin that has been released from erythrocytes, thereby inhibiting its oxidative activity. During this process, Haptoglobin sequesters the iron within Hemoglobin, preventing iron-utilizing bacteria from benefitting from hemolysis. This function suggests that Haptoglobin concentrations may increase in response to inflammation. The resulting Haptoglobin-Hemoglobin complex is then removed by the reticulo-endothelial system. Due to cleavage of a common precursor protein during protein synthesis, Haptoglobin consists of two α and two β chains, connected by disulfide bridges.
Alternative Name:
Bp, Haptoglobin alpha chain, Haptoglobin alpha(1S) beta, Haptoglobin alpha(2FS) beta, Haptoglobin beta chain, Haptoglobin, alpha polypeptide, Haptoglobin, beta polypeptide, HP, Hp2 alpha, HP2 ALPHA2, HP2ALPHA2, HPA1S, HPT, HPT, MGC111141,
Application Dilution: WB: 1:500 - 1:2000
Specificity: HP polyclonal antibody detects endogenous levels of HP protein.
Immunogen:
Recombinant full length Human Haptoglobin.
MW: ~ 45 kDa
Swis Prot.: P00738
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Haptoglobin (Hp) is a blood plasma protein that functions to bind free Hemoglobin that has been released from erythrocytes, thereby inhibiting its oxidative activity. During this process, Haptoglobin sequesters the iron within Hemoglobin, preventing iron-utilizing bacteria from benefitting from hemolysis. This function suggests that Haptoglobin concentrations may increase in response to inflammation. The resulting Haptoglobin-Hemoglobin complex is then removed by the reticulo-endothelial system. Due to cleavage of a common precursor protein during protein synthesis, Haptoglobin consists of two α and two β chains, connected by disulfide bridges.
Alternative Name:
Bp, Haptoglobin alpha chain, Haptoglobin alpha(1S) beta, Haptoglobin alpha(2FS) beta, Haptoglobin beta chain, Haptoglobin, alpha polypeptide, Haptoglobin, beta polypeptide, HP, Hp2 alpha, HP2 ALPHA2, HP2ALPHA2, HPA1S, HPT, HPT, MGC111141,
Application Dilution: WB: 1:500 - 1:2000
Specificity: HP polyclonal antibody detects endogenous levels of HP protein.
Immunogen:
Recombinant full length Human Haptoglobin.
MW: ~ 45 kDa
Swis Prot.: P00738
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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