HARS antibody (clone 1C8), anti-human
€435.00
In stock
SKU
AC-AT2317a
Catalog Number: AC-AT2317a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
Request Information AC-AT2317a">Request Information
Background:
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
Other Names:
Histidine--tRNA ligase, cytoplasmic, Histidyl-tRNA synthetase, HisRS, HARS, HRS
Antigen Type:
Recombinant Protein
Gene Name: HARS1 (HGNC:4816)
Gene ID: 3035
NCBI Accession: NP_001244969.1;NP_001244970.1;NP_001244971.1;NP_002100.2
Primary Accession: P12081
Other Accession: NM_002109
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
Other Names:
Histidine--tRNA ligase, cytoplasmic, Histidyl-tRNA synthetase, HisRS, HARS, HRS
Antigen Type:
Recombinant Protein
Gene Name: HARS1 (HGNC:4816)
Gene ID: 3035
NCBI Accession: NP_001244969.1;NP_001244970.1;NP_001244971.1;NP_002100.2
Primary Accession: P12081
Other Accession: NM_002109
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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