HARS polyclonal (N-term), anti-human, mouse, rat
€0.00
In stock
SKU
AC-AP7567a
Catalog Number: AC-AP7567a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB14816
Applications: WB, IHC-P
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB14816
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. HARS is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. This enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The protein is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
Other Names:
Histidine--tRNA ligase, cytoplasmic, Histidyl-tRNA synthetase, HisRS, HARS, HRS
Target/Specificity:
This HARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-78 amino acids from the N-terminal region of human HARS.
Antigen Region:
49-78
Antigen Type: Synthetic Peptide
Gene Name: HARS1 (HGNC:4816)
Gene ID: 3035
Primary Accession: P12081
NCBI Accession: NP_001244969.1;NP_001244970.1;NP_001244971.1;NP_002100.2
Other Accession: Q61035; Q2KI84
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. HARS is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. This enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The protein is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
Other Names:
Histidine--tRNA ligase, cytoplasmic, Histidyl-tRNA synthetase, HisRS, HARS, HRS
Target/Specificity:
This HARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-78 amino acids from the N-terminal region of human HARS.
Antigen Region:
49-78
Antigen Type: Synthetic Peptide
Gene Name: HARS1 (HGNC:4816)
Gene ID: 3035
Primary Accession: P12081
NCBI Accession: NP_001244969.1;NP_001244970.1;NP_001244971.1;NP_002100.2
Other Accession: Q61035; Q2KI84
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review