HASPIN Polyclonal Antibody

Background:
Serine/threonine-protein kinase that phosphorylates histone H3 at 'Thr-3' (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
germ cell associated 2, Germ cell-specific gene 2 protein, GSG2, H-haspin, Haploid germ cell-specific nuclear protein kinase, HASP, Serine/threonine-protein kinase haspin

Immunogen: Synthetic peptide of human HASPIN

Swissprot: Q8TF76
Gene Accession: NP114171

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.62 mg/mL
Dilution: IHC 1:20-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.