HAT1 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.

Synonyms: KAT1

Cellular Location: Cytoplasm Nucleus Nucleus matrix nucleoplasm

Immunogen:
Recombinant protein of human HAT1

Gene Symbol: HAT1

Gene ID: 8520

Swiss prot: O14929

Calculated MW: 50kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200, ChIP 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.