HAT1 polyclonal (N-term), anti-human

HAT1 polyclonal (N-term), anti-human

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In stock
SKU
AC-AP14563a
Catalog Number: AC-AP14563a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34525
Applications: WB
Datasheet

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Background:
The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.

Other Names:
Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase 1, HAT1, KAT1

Target/Specificity:
This HAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human HAT1.

Antigen Region:
21-50

Antigen Type: Synthetic Peptide

Gene Name: HAT1
Gene ID: 8520
Primary Accession: O14929
NCBI Accession: NP_003633.1
Other Accession: Q5M939; Q8BY71; NP_003633.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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