HAUSP / USP7 Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Microbiology

Synonyms:
USP7, HAUSP, TEF1

Immunogen: Recombinant fusion protein of human HAUSP / USP7 (NP_003461.2).

Swissprot: Q93009
Gene ID: 7874

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.