HAVCR2 Blocking Peptide (Center)

HAVCR2 Blocking Peptide (Center)

€363.00
In stock
SKU
AC-BP19990c
Catalog Number: AC-BP19990c
Size: 500 µg
Datasheet
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Background:
CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.

Other Names:
Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, TIM-3, T-cell membrane protein 3, HAVCR2, TIM3, TIMD3

Target/Specificity:
The synthetic peptide sequence is selected from aa 182-194 of HUMAN HAVCR2

Gene Name: HAVCR2

Gene ID: 84868
Primary Accession: Q8TDQ0
Other Accession: NP_116171.3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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