HAVCR2 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Synonyms: CD366, HAVcr-2, KIM-3, TIM3, TIMD-3, TIMD3, Tim-3

Cellular Location: Membrane Single-pass type I membrane protein

Immunogen:
A synthetic peptide of human HAVCR2

Gene Symbol: HAVCR2

Gene ID: 84868

Swiss prot: Q8TDQ0

Calculated MW: 33kDa

Recommended dilution:
WB 1:500-1000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.