HAX1 antibody (clone 1D2), anti-human
€435.00
In stock
SKU
AC-AT2320a
Catalog Number: AC-AT2320a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT2320a">Request Information
Background:
The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
Other Names:
HCLS1-associated protein X-1, HS1-associating protein X-1, HAX-1, HS1-binding protein 1, HSP1BP-1, HAX1, HS1BP1
Antigen Type:
Recombinant Protein
Gene Name: HAX1
Gene ID: 10456
NCBI Accession: NP_001018238.1;NP_006109.2
Primary Accession: O00165
Other Accession: NM_006118
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
Other Names:
HCLS1-associated protein X-1, HS1-associating protein X-1, HAX-1, HS1-binding protein 1, HSP1BP-1, HAX1, HS1BP1
Antigen Type:
Recombinant Protein
Gene Name: HAX1
Gene ID: 10456
NCBI Accession: NP_001018238.1;NP_006109.2
Primary Accession: O00165
Other Accession: NM_006118
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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