HAX1 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS7615
Background:
The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
Alternative Name:
HAX 1, HAX-1, HAX1, HAX1_HUMAN, Hax1a, HCLS1 and PKD2 associated protein, HCLS1 associated protein, HCLS1 associated protein X 1, HCLS1-associated protein X-1, HCLSBP1, HS 1 associated protein X 1, HS 1 binding protein, HS1 associating protein X 1, HS1 binding protein 1, HS1 binding protein, HS1-associating protein X-1, HS1-binding protein 1, HS1BP1, HSP1BP-1, OTTHUMP00000034190, SCN3,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100
Specificity: HAX1 polyclonal antibody detects endogenous levels of HAX1 protein.
Immunogen:
Recombinant full length Human HAX1.
MW: ~31 kDa
Swis Prot.: O00165
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
Alternative Name:
HAX 1, HAX-1, HAX1, HAX1_HUMAN, Hax1a, HCLS1 and PKD2 associated protein, HCLS1 associated protein, HCLS1 associated protein X 1, HCLS1-associated protein X-1, HCLSBP1, HS 1 associated protein X 1, HS 1 binding protein, HS1 associating protein X 1, HS1 binding protein 1, HS1 binding protein, HS1-associating protein X-1, HS1-binding protein 1, HS1BP1, HSP1BP-1, OTTHUMP00000034190, SCN3,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100
Specificity: HAX1 polyclonal antibody detects endogenous levels of HAX1 protein.
Immunogen:
Recombinant full length Human HAX1.
MW: ~31 kDa
Swis Prot.: O00165
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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