HAX1 polyclonal, anti-human, mouse

Background:
The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms: HCLSBP1, HS1BP1, SCN3

Cellular Location: Cytoplasmic vesicle Endoplasmic reticulum Mitochondrion Nucleus membrane Sarcoplasmic reticulum

Immunogen:
Recombinant protein of human HAX1

Gene Symbol: HAX1

Gene ID: 10456

Swiss prot: O00165

Calculated MW: 32kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:10-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.