HBA2 polyclonal (Center), anti-human, mouse
€0.00
In stock
SKU
AC-AP9414c
Catalog Number: AC-AP9414c
Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB24041
Applications: WB, FC
Datasheet
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Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB24041
Applications: WB, FC
Datasheet
Request Information
Background:
HBA2 located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
Other Names:
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain, HBA1
Target/Specificity:
This HBA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-128 amino acids from the Central region of human HBA2.
Antigen Region:
100-128
Antigen Type: Synthetic Peptide
Gene Name: HBA1
Gene ID: 3039;3040
Primary Accession: P69905
NCBI Accession: NP_000508.1;NP_000549.1
Other Accession: P21767
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
HBA2 located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
Other Names:
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain, HBA1
Target/Specificity:
This HBA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-128 amino acids from the Central region of human HBA2.
Antigen Region:
100-128
Antigen Type: Synthetic Peptide
Gene Name: HBA1
Gene ID: 3039;3040
Primary Accession: P69905
NCBI Accession: NP_000508.1;NP_000549.1
Other Accession: P21767
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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