HBG1 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP13696c
Background:
The gamma globin genes (HBG1 and HBG2) are normallyexpressed in the fetal liver, spleen and bone marrow. Two gammachains together with two alpha chains constitute fetal hemoglobin(HbF) which is normally replaced by adult hemoglobin (HbA) atbirth. In some beta-thalassemias and related conditions, gammachain production continues into adulthood. The two types of gammachains differ at residue 136 where glycine is found in the G-gammaproduct (HBG2) and alanine is found in the A-gamma product (HBG1).The former is predominant at birth. The order of the genes in thebeta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta-- beta--3'.
Other Names:
Hemoglobin subunit gamma-1, Gamma-1-globin, Hb F Agamma, Hemoglobin gamma-1 chain, Hemoglobin gamma-A chain, HBG1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13696c was selected from the Center region of HBG1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HBG1
Gene ID: 3047
Primary Accession: P69891
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The gamma globin genes (HBG1 and HBG2) are normallyexpressed in the fetal liver, spleen and bone marrow. Two gammachains together with two alpha chains constitute fetal hemoglobin(HbF) which is normally replaced by adult hemoglobin (HbA) atbirth. In some beta-thalassemias and related conditions, gammachain production continues into adulthood. The two types of gammachains differ at residue 136 where glycine is found in the G-gammaproduct (HBG2) and alanine is found in the A-gamma product (HBG1).The former is predominant at birth. The order of the genes in thebeta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta-- beta--3'.
Other Names:
Hemoglobin subunit gamma-1, Gamma-1-globin, Hb F Agamma, Hemoglobin gamma-1 chain, Hemoglobin gamma-A chain, HBG1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13696c was selected from the Center region of HBG1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HBG1
Gene ID: 3047
Primary Accession: P69891
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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