HBO1 polyclonal antibody, anti-human, mouse, rat

Background:
KAT7 is a gene on chromosome 17q21.2 that encodes a component of the HBO1 complex which is responsible for the bulk of histone H4 acetylation. Histone acetyltransferase KAT7 specifically represses AR-mediated transcription; it may regulate DNA replication by chromatin acetylation and act as a coactivator of TP53-dependent transcription.

Research Area: Epigenetics and Nuclear Signaling

Synonyms: KAT7, HBO1, HBOa, MYST2, Histone acetyltransferase KAT7, Histone acetyltransferase binding to ORC1, Lysine acetyltransferase 7, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2, MYST-2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year