HBP1 (Phospho Ser402) polyclonal antibody, anti-human, mouse, rat

Background:
Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.,Contains 1 AXH domain.,Contains 1 HMG box DNA-binding domain.,subunit:Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.,

Research Area: Cardiovascular, Metabolism, Signal transduction, Epigenetics and nuclear signaling, Stem cells

Synonyms: HMG box-containing protein 1, HBP1, HMG box-containing protein 1, HMG box transcription factor 1, High mobility group box transcription factor 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year