HBS1L polyclonal (Center), anti-human, mouse

HBS1L polyclonal (Center), anti-human, mouse

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In stock
SKU
AC-AP18556C
Catalog Number: AC-AP18556C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB38809
Applications: WB
Datasheet

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Background:
This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Other Names:
HBS1-like protein, ERFS, HBS1L, HBS1, KIAA1038

Target/Specificity:
This HBS1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 460-486 amino acids from the Central region of human HBS1L.

Antigen Region:
460-486

Antigen Type: Synthetic Peptide

Gene Name: HBS1L {ECO:0000303|PubMed:28204585, ECO:0000312|HGNC:HGNC:4834}
Gene ID: 10767
Primary Accession: Q9Y450
NCBI Accession: NP_001138630.1;NP_001138679.1;NP_006611.1
Other Accession: Q6AXM7; Q69ZS7; Q2KHZ2; NP_001138630.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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