HCK polyclonal, anti-human, mouse

Background:
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.

Synonyms: JTK9, p59Hck, p61Hck

Cellular Location: Cell junction Cell membrane Cell projection Cytoplasm Cytoplasmic vesicle Golgi apparatus Lipid-anchor Lysosome Membrane Nucleus caveola cytoskeleton cytosol cytosol focal adhesion podosome membrane secretory vesicle

Immunogen:
Recombinant protein of human HCK

Gene Symbol: HCK

Gene ID: 3055

Swiss prot: P08631

Calculated MW: 60kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:10-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.