HCK Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.

Research Area: Cancer, Immunology, Signal Transduction

Synonyms:
HCK, JTK9, p59Hck, p61Hck

Immunogen: Recombinant fusion protein of human HCK (NP_001165600.1).

Swissprot: P08631
Gene ID: 3055

Calculated MW: 57 kDa/59 kDa
Observed MW: 55-60 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.