HCN1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1, also known as HAC-2 or BCNG-1, is a protein that in humans is encoded by the HCN1 gene. It is mapped to 5p12. The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for sour tastes. Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. It may mediates responses to sour stimuli.

Description:
Rabbit IgG polyclonal antibody for Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (HCN1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
BCNG-1 antibody, BCNG1 antibody, Brain cyclic nucleotide gated channel 1 antibody, Brain cyclic nucleotide-gated channel 1 antibody, HAC 2 antibody, HAC2 antibody, HCN1 antibody, HCN1_HUMAN antibody, Hyperpolarization activated cyclic nucleotide gated potassium channel 1 antibody, Potassium channel, voltage-gated, brain, 1 antibody, Potassium/sodium hyperpolarization activated cyclic nucleotide gated channel 1 antibody, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human HCN1 recombinant protein (Position: E618-L890). Human HCN1 shares 82% amino acid (aa) sequence identity with both mouse and rat HCN1.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.