HDAC1 middle region polyclonal, anti-human, mouse, rat, rabbit, zebrafish, pig, dog, guinea pig, horse, bovine, yeast

Background:
This is a rabbit polyclonal antibody against HDAC1. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein.

Other Names:
Histone deacetylase 1, HD1, HDAC1, RPD3L1

Target/Specificity:
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Immunogen:
The immunogen for anti-HDAC1 antibody: synthetic peptide directed towards the middle region of human HDAC1

Gene Name:
HDAC1 {ECO:0000303|PubMed:10846170, ECO:0000312|HGNC:HGNC:4852}
Gene Name:
3065
Swissprot ID: Q13547
NCBI Accession:
NP_004955
Primary Accession: Q13547
Other Accession: Q13547;NP_004955;NM_004964
Purification: Affinity Purified
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.