HDAC1 polyclonal, anti-human, rat

Quantity: 100 µg

Background:
Histone deacetylase 1 is an enzyme that in humans is encoded by the HDAC1 gene. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. Furukawa et al.(1996) mapped RPD3L1 to 1p34.1 by fluorescence in situ hybridization.

Description:
Rabbit IgG polyclonal antibody for Histone deacetylase 1 (HDAC1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
DKFZp686H12203 antibody, GON 10 antibody, HD 1 antibody, HD1 antibody, HDAC 1 antibody, HDAC1 antibody, hdac1: histone deacetylase 1 antibody, HDAC1_HUMAN antibody, Histone deacetylase 1(HD1) antibody, Histone deacetylase 1 antibody, Reduced potassium dependency yeast homolog like 1 antibody, RPD3(reduced potassium dependency yeast homolog) like 1 antibody, RPD3(reduced potassium dependency) antibody, RPD3 antibody, RPD3L1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC1(1-14aa MAQTQGTRRKVCYY), identical to the related mouse and rat sequences.A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC1(1-14aa MAQTQGTRRKVCYY), identical to the related mouse and rat sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.