HDAC1 Polyclonal Antibody

Background:
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem Cells

Synonyms:
DKFZp686H12203, GON 10, HD1, HDAC 1, HDAC1, HDAC1, Histone deacetylase 1, Reduced potassium dependency yeast homolog like 1, RPD3, RPD3L1

Immunogen: Recombinant protein corresponding to Mouse HDAC1

Swissprot: Q13547,O09106,Q4QQW4

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 310 μg/mL
Dilution: IHC 1:200-1:1000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.