HDAC1 polyclonal (N-term), anti-human, mouse, rat
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In stock
SKU
AC-AP1101b
Catalog Number: AC-AP1101b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB5639
Applications: WB, IF
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB5639
Applications: WB, IF
Datasheet
Request Information
Background:
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Other Names:
Histone deacetylase 1, HD1, HDAC1, RPD3L1
Target/Specificity:
This HDAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HDAC1.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: HDAC1 {ECO:0000303|PubMed:10846170, ECO:0000312|HGNC:HGNC:4852}
Gene ID: 3065
Primary Accession: Q13547
NCBI Accession: NP_004955.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Other Names:
Histone deacetylase 1, HD1, HDAC1, RPD3L1
Target/Specificity:
This HDAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HDAC1.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: HDAC1 {ECO:0000303|PubMed:10846170, ECO:0000312|HGNC:HGNC:4852}
Gene ID: 3065
Primary Accession: Q13547
NCBI Accession: NP_004955.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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