HDAC11 polyclonal (N-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP1111a
Catalog Number: AC-AP1111a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2588
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2588
Applications: WB, IHC-P
Datasheet
Request Information
Background:
HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. The predominantly nuclear HDAC11, which interacts with HDAC6, is weakly expressed in most tissues, and strongly expressed in brain, heart, skeletal muscle, kidney and testis. Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.
Other Names:
Histone deacetylase 11, HD11, HDAC11
Target/Specificity:
This HDAC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HDAC11.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: HDAC11
Gene ID: 79885
Primary Accession: Q96DB2
NCBI Accession: NP_001129513.1;NP_079103.2
Other Accession: NP_079103
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. The predominantly nuclear HDAC11, which interacts with HDAC6, is weakly expressed in most tissues, and strongly expressed in brain, heart, skeletal muscle, kidney and testis. Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.
Other Names:
Histone deacetylase 11, HD11, HDAC11
Target/Specificity:
This HDAC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HDAC11.
Antigen Region:
1-30
Antigen Type: Synthetic Peptide
Gene Name: HDAC11
Gene ID: 79885
Primary Accession: Q96DB2
NCBI Accession: NP_001129513.1;NP_079103.2
Other Accession: NP_079103
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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