HDAC2 (clone 2D9) mouse monoclonal, anti-human, mouse, rat, monkey

Backgroud: In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA.

Synonyms: HDAC2, Histone deacetylase 2, HD2

Gene Name: HDAC2

Gene ID: 3066

SwissProt ID: Q92769

Purification: Affinity Purified

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.