HDAC2 Polyclonal Antibody

Background:
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem Cells

Synonyms:
D10Wsu179e, HD 2, HD2, HDAC 2, Hdac2, HDAC2, Histone deacetylase 2 (HD2), Histone deacetylase 2, OTTHUMP00000017046, OTTHUMP00000227077, OTTHUMP00000227078, RPD3, transcriptional regulator homolog RPD3, YAF1, YY1 associated factor 1, YY1 transcription factor binding protein, Yy1bp

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse HDAC2

Swissprot: P70288,Q92769

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 1.8 mg/mL
Dilution: IHC 1:300-1:1000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.