HDAC2 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP1102b
Catalog Number: AC-AP1102b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB5718
Applications: WB, IF, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB5718
Applications: WB, IF, IHC-P
Datasheet
Request Information
Background:
Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly conserved from yeast to human.
Other Names:
Histone deacetylase 2, HD2, HDAC2
Target/Specificity:
This HDAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 456-488 amino acids from the C-terminal region of human HDAC2.
Antigen Region:
456-488
Antigen Type: Synthetic Peptide
Gene Name: HDAC2 {ECO:0000303|PubMed:10545197, ECO:0000312|HGNC:HGNC:4853}
Gene ID: 3066
Primary Accession: Q92769
NCBI Accession: NP_001518.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly conserved from yeast to human.
Other Names:
Histone deacetylase 2, HD2, HDAC2
Target/Specificity:
This HDAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 456-488 amino acids from the C-terminal region of human HDAC2.
Antigen Region:
456-488
Antigen Type: Synthetic Peptide
Gene Name: HDAC2 {ECO:0000303|PubMed:10545197, ECO:0000312|HGNC:HGNC:4853}
Gene ID: 3066
Primary Accession: Q92769
NCBI Accession: NP_001518.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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