HDAC3 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13297b
Background:
Histones play a critical role in transcriptionalregulation, cell cycle progression, and developmental events.Histone acetylation/deacetylation alters chromosome structure andaffects transcription factor access to DNA. The protein encoded bythis gene belongs to the histone deacetylase/acuc/apha family. Ithas histone deacetylase activity and represses transcription whentethered to a promoter. It may participate in the regulation oftranscription through its binding with the zinc-fingertranscription factor YY1. This protein can also down-regulate p53function and thus modulate cell growth and apoptosis. This gene isregarded as a potential tumor suppressor gene. [provided byRefSeq].
Other Names:
Histone deacetylase 3, HD3, RPD3-2, SMAP45, HDAC3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13297b was selected from the C-term region of HDAC3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HDAC3
Gene ID: 8841
Primary Accession: O15379
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Histones play a critical role in transcriptionalregulation, cell cycle progression, and developmental events.Histone acetylation/deacetylation alters chromosome structure andaffects transcription factor access to DNA. The protein encoded bythis gene belongs to the histone deacetylase/acuc/apha family. Ithas histone deacetylase activity and represses transcription whentethered to a promoter. It may participate in the regulation oftranscription through its binding with the zinc-fingertranscription factor YY1. This protein can also down-regulate p53function and thus modulate cell growth and apoptosis. This gene isregarded as a potential tumor suppressor gene. [provided byRefSeq].
Other Names:
Histone deacetylase 3, HD3, RPD3-2, SMAP45, HDAC3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13297b was selected from the C-term region of HDAC3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HDAC3
Gene ID: 8841
Primary Accession: O15379
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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