HDAC3 antibody (clone 2A3), anti-human, mouse, rat

HDAC3 antibody (clone 2A3), anti-human, mouse, rat

€435.00
In stock
SKU
AC-AT2339a
Catalog Number: AC-AT2339a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IFhttps://www.abcepta.com/products/pdf_download/AT2339a-HDAC3-Antibody-monoclonal-M03">Request Information AC-AT2339a">Request Information
Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Other Names:
Histone deacetylase 3, HD3, RPD3-2, SMAP45, HDAC3

Antigen Type:
Recombinant Protein

Gene Name: HDAC3
Gene ID: 8841
NCBI Accession: NP_003874.2
Primary Accession: O15379
Other Accession: NM_003883
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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