HDAC3 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP1103a
Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. HDAC3 isregarded as a potential tumor suppressor gene.
Other Names:
Histone deacetylase 3, HD3, RPD3-2, SMAP45, HDAC3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1103a was selected from the N-term region of human HDAC3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HDAC3
Gene ID: 8841
Primary Accession: O15379
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. HDAC3 isregarded as a potential tumor suppressor gene.
Other Names:
Histone deacetylase 3, HD3, RPD3-2, SMAP45, HDAC3
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1103a was selected from the N-term region of human HDAC3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HDAC3
Gene ID: 8841
Primary Accession: O15379
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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