HDAC3 (clone 3G3) mouse monoclonal, anti-human, mouse, rat

Backgroud: HDAC3 is a nuclear and cytoplasmic protein that deacetylates both histone (H2A, H3, H4) and non-histone substrates (RelA, SRY, p53, MEF2, PCAF and p300/CBP). HDAC3 deacetylase activity is stimulated by interactions with the N-CoR and SMRT co-repressor proteins. Together, these three proteins form a functional complex that represses transcription associated with nuclear hormone receptors and other transcription factors, including Rev-Erb, COUP-TF, DAX1, MAD and Pit-1.

Synonyms: HDAC3, Histone deacetylase 3, HD3, RPD3-2, SMAP45

Gene Name: HDAC3

Gene ID: 8841

SwissProt ID: O15379

Purification: Affinity Purified

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.