HDAC4 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13715b
Background:
Histones play a critical role in transcriptionalregulation, cell cycle progression, and developmental events.Histone acetylation/deacetylation alters chromosome structure andaffects transcription factor access to DNA. The protein encoded bythis gene belongs to class II of the histone deacetylase/acuc/aphafamily. It possesses histone deacetylase activity and repressestranscription when tethered to a promoter. This protein does notbind DNA directly, but through transcription factors MEF2C andMEF2D. It seems to interact in a multiprotein complex with RbAp48and HDAC3.
Other Names:
Histone deacetylase 4, HD4, HDAC4, KIAA0288
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13715b was selected from the C-term region of HDAC4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HDAC4 (HGNC:14063)
Gene ID: 9759
Primary Accession: P56524
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Histones play a critical role in transcriptionalregulation, cell cycle progression, and developmental events.Histone acetylation/deacetylation alters chromosome structure andaffects transcription factor access to DNA. The protein encoded bythis gene belongs to class II of the histone deacetylase/acuc/aphafamily. It possesses histone deacetylase activity and repressestranscription when tethered to a promoter. This protein does notbind DNA directly, but through transcription factors MEF2C andMEF2D. It seems to interact in a multiprotein complex with RbAp48and HDAC3.
Other Names:
Histone deacetylase 4, HD4, HDAC4, KIAA0288
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13715b was selected from the C-term region of HDAC4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HDAC4 (HGNC:14063)
Gene ID: 9759
Primary Accession: P56524
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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