HDAC4 polyclonal (C-term), anti-human

HDAC4 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP13715b
Catalog Number: AC-AP13715b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33667
Applications: IF, IHC-P, WB
Datasheet

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Background:
Histones play a critical role in transcriptionalregulation, cell cycle progression, and developmental events.Histone acetylation/deacetylation alters chromosome structure andaffects transcription factor access to DNA. The protein encoded bythis gene belongs to class II of the histone deacetylase/acuc/aphafamily. It possesses histone deacetylase activity and repressestranscription when tethered to a promoter. This protein does notbind DNA directly, but through transcription factors MEF2C andMEF2D. It seems to interact in a multiprotein complex with RbAp48and HDAC3.

Other Names:
Histone deacetylase 4, HD4, HDAC4, KIAA0288

Target/Specificity:
This HDAC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1049-1077 amino acids from the C-terminal region of human HDAC4.

Antigen Region:
1049-1077

Antigen Type: Synthetic Peptide

Gene Name: HDAC4 (HGNC:14063)
Gene ID: 9759
Primary Accession: P56524
NCBI Accession: NP_006028.2
Other Accession: NP_006028.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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