HDAC5 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP1105b
Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been noted for this gene.
Other Names:
Histone deacetylase 5, HD5, Antigen NY-CO-9, HDAC5, KIAA0600
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1105b was selected from the Center region of human HDAC5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HDAC5
Gene ID: 10014
Primary Accession: Q9UQL6
Other Accession: NP_005465
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been noted for this gene.
Other Names:
Histone deacetylase 5, HD5, Antigen NY-CO-9, HDAC5, KIAA0600
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1105b was selected from the Center region of human HDAC5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HDAC5
Gene ID: 10014
Primary Accession: Q9UQL6
Other Accession: NP_005465
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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