HDAC5 antibody (clone 4G2), anti-human

HDAC5 antibody (clone 4G2), anti-human

€435.00
In stock
SKU
AC-AT2340a
Catalog Number: AC-AT2340a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
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Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

Other Names:
Histone deacetylase 5, HD5, Antigen NY-CO-9, HDAC5, KIAA0600

Antigen Type:
Recombinant Protein

Gene Name: HDAC5
Gene ID: 10014
NCBI Accession: NP_001015053.1;NP_005465.2
Primary Accession: Q9UQL6
Other Accession: BC051824
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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