HDAC6 (clone 3B2) mouse monoclonal, anti-human, rat

Backgroud: Involved in the regulation of many cellular processes, including cell migration, immune synapse formation, viral infection, and degradation of misfolded proteins. HDAC6 binds to both poly-ubiquitinated misfolded proteins and dynein motors, facilitating the transport of misfolded proteins to the aggresome. Required for subsequent recruitment of the autophagic machinery and clearance of aggresomes from the cell. Plays a key role in the protection against the deleterious effects of pathological protein aggregation that occurs in various diseases.

Synonyms: HDAC6, KIAA0901, JM21, Histone deacetylase 6, HD6

Gene Name: HDAC6

Gene ID: 10013

SwissProt ID: Q9UBN7

Purification: Affinity Purified

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.