HDAC6/Histone Deacetylase 6 monoclonal, anti-human
€455.00
In stock
SKU
AC-ABO13696
Catalog Number: AC-ABO13696
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IF, ICC, IP
Datasheet
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Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC, IF, ICC, IP
Datasheet
Request Information
Description: Anti-HDAC6/Histone Deacetylase 6 Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.
Protein Function:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer..
Other Names: Histone deacetylase 6, HD6, 3.5.1.98, Protein deacetylase HDAC6, 3.5.1.-, Tubulin-lysine deacetylase HDAC6, 3.5.1.-, HDAC6 {ECO:0000303|PubMed:10220385, ECO:0000312|HGNC:HGNC:14064}
Clone Name(s):
Clone: HEE-8
Subcellular Localization: Nucleus. Cytoplasm. Perikaryon. Cell projection, dendrite. Cell projection, axon. It is mainly cytoplasmic, where it is associated with microtubules.
Gene ID: 10013
Immunogen: A synthesized peptide derived from human HDAC6
Calculated MW: 131419
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Function:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer..
Other Names: Histone deacetylase 6, HD6, 3.5.1.98, Protein deacetylase HDAC6, 3.5.1.-, Tubulin-lysine deacetylase HDAC6, 3.5.1.-, HDAC6 {ECO:0000303|PubMed:10220385, ECO:0000312|HGNC:HGNC:14064}
Clone Name(s):
Clone: HEE-8
Subcellular Localization: Nucleus. Cytoplasm. Perikaryon. Cell projection, dendrite. Cell projection, axon. It is mainly cytoplasmic, where it is associated with microtubules.
Gene ID: 10013
Immunogen: A synthesized peptide derived from human HDAC6
Calculated MW: 131419
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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