HDAC6 polyclonal, anti-human, mouse, rat antibody
€310.00
In stock
SKU
AC-ABV10451-100
Catalog Number: AC-ABV10451-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC
Datasheet
Request Information
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC
Datasheet
Request Information
Background:
Human HDAC6 (1215 a.a. residues) possesses two separate putative catalytic domains, both of which are fully functional and contribute independently to the overall activity of HDAC6. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. HDAC6 may participate in coordinating expression of a group of genes involved in the remoldeling of chromatin during cell differentiation.
Other Names:
HD6, HDAC-6, histone deacetylase 6, JM21
Primary Accession: Q9Z2V5
Gene Name: Hdac6 {ECO:0000312|MGI:MGI:1333752}
Gene ID: 15185
Concentration (mg/ml): 0.2 mg/ml
Human HDAC6 (1215 a.a. residues) possesses two separate putative catalytic domains, both of which are fully functional and contribute independently to the overall activity of HDAC6. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. HDAC6 may participate in coordinating expression of a group of genes involved in the remoldeling of chromatin during cell differentiation.
Other Names:
HD6, HDAC-6, histone deacetylase 6, JM21
Primary Accession: Q9Z2V5
Gene Name: Hdac6 {ECO:0000312|MGI:MGI:1333752}
Gene ID: 15185
Concentration (mg/ml): 0.2 mg/ml
| Is Featured? | No |
|---|
Write Your Own Review