HDAC6 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6784
Background:
HDAC6 is a member of the class II mammalian histone deacetylases. Human HDAC6 is composed of 1215 amino acid residues. It possesses two separate putative catalytic domains. Both catalytic domains are fully functional HDACs and contribute independently to the overall activity of HDAC6 protein. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function.
Alternative Name:
Histone deacetylase 6, HD6, HDAC 6, KIAA0901, JM21
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IP: 1:20 - 1:50
Specificity: HDAC6 polyclonal antibody detects endogenous levels of HDAC6 protein.
Immunogen:
Recombinant full length Human HDAC6.
MW: ~ 135 kDa
Swis Prot.: Q9UBN7
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
HDAC6 is a member of the class II mammalian histone deacetylases. Human HDAC6 is composed of 1215 amino acid residues. It possesses two separate putative catalytic domains. Both catalytic domains are fully functional HDACs and contribute independently to the overall activity of HDAC6 protein. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function.
Alternative Name:
Histone deacetylase 6, HD6, HDAC 6, KIAA0901, JM21
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IP: 1:20 - 1:50
Specificity: HDAC6 polyclonal antibody detects endogenous levels of HDAC6 protein.
Immunogen:
Recombinant full length Human HDAC6.
MW: ~ 135 kDa
Swis Prot.: Q9UBN7
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review