HDAC6 polyclonal, anti-human, mouse, rat

Background:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Synonyms: CPBHM, HD6, JM21, PPP1R90

Cellular Location: Cell projection Cytoplasm Nucleus Perikaryon axon dendrite

Immunogen:
Recombinant protein of human HDAC6

Gene Symbol: HDAC6

Gene ID: 10013

Swiss prot: Q9UBN7

Calculated MW: 131kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200, IP 1:20-50,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.